Arimidex was the first aromatase inhibitor available.
It is therefore the most well known among anti aromatases and the one doctors have most experience with.
Anastrozole has been tested for reducing estrogens, including estradiol, in men.Excess estradiol in men can cause benign prostatic hyperplasia,gynecomastia, and symptoms of hypogonadism. It can also contribute to increased risk of stroke, heart attack, chronic inflammation, prostate enlargement and prostate cancer.athlets and body buildersuse anastrozole as part of their steroid cycleto reduce and prevent symptoms of excess estrogen–gynecomastia, emotional lability and water retention.Study data suggests dosages of 0.5mg to 1mg a day reduce serum estradiol approx. 50% in men, which differs in postmenopausal women.